I am trying to locate Jane Clark(e) of Chaddesden, Derbyshire.
Christened in St Mary’s Church, Chaddesden 25th May 1823
Parents:
William Clark(e), Farm Labourer (abt 1791 - 1867)
and Ann (abt 1795 - 1879)
Jane had a child, Reuben Clarke, out of wedlock - Born 15th June 1843 and Christened 27 Dec 1846, (in Chaddesden)
No idea who his father is.
Reuben was living with his grandparents in the 1851 Census. No sign of Jane.
I am assuming she got married, moved away or died. I have checked potential marriages, census’ and death records but have not been able to move this research forward.
Any help would be very much appreciated. Thank you
Where was your Jane Clark in 1841?
She's not with the family in 1841 Chaddesden Village
William 50, Ann 45 , Andrew 15, Emma 14, German 9 and Henery 6
1841 https://www.familysearch.org/ark:/61903/1:1:M7SG-93N?lang=en
And as you mentioned not with her parents, brother and her son in 1851
1851 https://www.familysearch.org/ark:/61903/1:1:SGD8-G6F?lang=en
Could she have left the UK after birth Reuben? Have you checked passenger lists?
Who is Reuben with in 1861?
in 1861 he is working for John Barker, Farmer of 220 acres, as a 'servant' in Chaddesden.
Luckily they were accurate with Reubens, age and place of birth which helped to find him relatively quickly.
In 1871 he was Married to Emma (Carrington) with two children, still living in Chaddesden
Reuben's marriage on 11 Nov 1867 to Emma Carrington
his father named as John occ boatman 
Thank you for looking into all these different potentials Ladyhawk, it is very much appreciated. I will follow up the potential leads that you have found for me.
I did have a brief look in the past at whether Jane may have left the country, but given her fairly common name, I didn't get very far. Maybe an angle to review again, there may be more records available online now.
With regards to Reuben's marriage certificate where he named his father as John Clarke. After locating him baptism record I figured he just took his mother's name and turned it into John so he didn't leave the section blank?? the fact he said that he was a 'Bank Man' is interesting though, given that his Grandfather William was never described as such...maybe that was his actual fathers profession?