In one branch, I have a couple who had 9 children. I've found 8 of them, I suspect the missing child was probably a premature birth which was never registered.
The couple lost 2 children in 1875, one aged 2 years, the other aged 6 months. In 1878 they lost a 2 month old baby. The eldest, a girl, died of rheumatic fever in 1889 aged 18. But their worst year was 1887. That year started off with the loss of a 3 year old boy in January, followed by the death of another boy in March. That was quickly followed by the death of the father, John, in April at the age of 46. Finally, in August, another girl, aged 8, died. The mother lived until 1919, the remaining son living into the 1920s.
I honestly don't know how they, or others, coped with so much loss.