Thank you everyone for your suggestions - I suppose I'm inclined more towards the TB diagnosis, though, saying that, it is and can only ever remain speculative. As was noted above, in 1899, I think TB would be more likely in a 30 year old than an advanced lung tumour. While it's certainly possible that she had another condition, TB was endemic at the time - I've also read various commentaries that suggest that women and younger people were disproportionally effected by the disease. But, it's a guess, albeit, a reasonable guess I think.