The parish entry for Joseph Jefferson and Hannah Barnes marriage at Aikton says that Hannah was of the parish and a spinster and Joseph was from Wigton. After "Joseph Jefferson of the parish of Wigton" which I would have thought it would have said batchelor/widower, but it looks to me like "surjourn", (temporary stay?). Could he be "your Joseph" and staying with family/friends in Wigton?
(I've tried to attached a jpg of it but keep getting an error message)
With regard to the "Jeffersons of Howe End", this seems to a well established and large family of the area, with many branches. There's a few wills with the name and address and the CASCAT catalogue seems to have a few entry's. While they maybe related there seems to be lots of info that would suggest they have been farming in the area for a long time, so I think you're right about Joseph Jefferson and Hannah Mark not being your Joseph.