Unfortunately there is nothing written on the back of the photo. John H. Flohr, the husband of the older woman and father of the two younger women, who is standing closest to the entrance into the building, was originally from Hamburg, so it's possible this was taken there, but that was also an industrial city and I'm not aware of him ever having gone back. That said, I understand he travelled at least once each to Zurich and Weisbaden with some family members.
The two men in the foreground must have been either friends, employees or relatives of John Flohr. The two daughters only married once each, and to the same man (successively); he was closer to them in age.