The sheer numbers of cM in the range does point towards a 3C or 2C1R level as having a reasonable probability.
Does any of the matches link to any of the other matches?
In my own tree I have linked to my own matches with the relationships I quote above.
Again using my own highest cM match I have a tree of 600 build around them and 12 other cM matches linked into the tree but as yet no link to me.
My Great Grandmother’s father was unknown, then I had a high cM match that linked to an Italian family and I found a high probability who my GGGF was. I have over 100 likely Italian Cousins and of those with trees then a specific region is common to them all.
As I wrote in my first post, do have them undertake more DNA tests with others especially Ancestry.