John Little and his wife Jean Birrell are named on a gravestone at Gretna Old Church; when John Little died in 1845 he was of "Guards Mill" - the Carlisle Journal reports a marriage in 1844 in Kirkandrews on Esk between Robert Benson, draper of Carlisle, to Mary Ann Little, daughter of Mr John Little of Guards Mill.
(I think Guards Mill is actually on the English side of the border though).