There are so many Sykes families I dont know which one to go with.. Is this church Spitalfields near to Mile End Old Town ?
Yes this marriage is right in the Stepney – Mile end - Whitechapel area, which is why I brought it to your attention.
Marriage at Christ Church Spitalfields, Tower Hamlets on 29 Jan 1809
Between John SYKES (bachelor) and Mary SYKES (spinster)
Both of this parish.
Both sign their names.
Witnesses – George Ashton (church cleric) & Caroline Sykes
There is a family tree that has John Sykes married to Mary Tibbetts but I am reluctant to follow that one.
The marriage of John Sykes to Mary Tibbets was in 1787 in Bermondsey.
It doesn't look like a very good option to me.
Where are the children born in the first 20 years of their marriage?
I think it is best to ignore other trees all copying mistakes from each other, and do your own research.