In 1861 246/118/20
Thomas is 31 yrs p, b Bethnal Green and Mary A is 41 yrs. She is born Bishopsgate. 
This looks quite good 
Mary Ann Sadler born 12th December 1839 and baptised 15th January 1840
Parents Thomas Sadler and Ruth Sadler (Maslin) address 9 North Place, Kingsland Road 
Thomas is a Chemist  

The baptism is Non-conformist, Bishopsgate.
You could try to follow that up to check.