locating Semple concentrations might be helped by this addition
1823-1837 Tithes Applotment Books based upon the index work of the Irish Genealogy Hub’s 
listing for each parish in Northern Ireland, which are quicker to lookup if you know the parish!
The relevant original books are in the Public Record Office of Northern Ireland (PRONI) Belfast
Sample, Hu.-Townland: Carrenbrock Year: 1833-Templecorran-Antrim
Sample, James-Townland: Killykergin Year: 1832-Aghadowey -Derry
Sample, James-Townland: Luney Year: 1827-Desertmartin-Derry
Sample, Jas.-Townland: Hogstown Year: 1834-Donaghadee-Down
Sample, John-Townland: Killykergin Year: 1832-Aghadowey -Derry
Sample, John-Townland: Rosegarland Year: 1827-Desertmartin-Derry
Semple, C.-Tl: Garvetagh Upper Yr: 1834-Ardstraw-Tyrone
Semple, Charles-T: Killen Y: 1826-Termonamongan-Tyrone
Semple, Francis-T: Laught Y: 1826-Termonamongan-Tyrone
Semple, George-Tl: Garveteagh Upper Yr: 1834-Ardstraw-Tyrone
Semple, Hugh-Townland: Loughan Year: 1834-Kildollagh-Derry
Semple, James-T: Mulnabreen Y: 1826-Termonamongan-Tyrone
Semple, James-Townland: Derryduff Year: 1834-Dungiven-Derry
Semple, James-Townland: Dromore Year: 1834-Clonallan-Down
Semple, James-Townland: Narrowwater Year: 1834-Clonallan-Down
Semple, Jno.-Tl: Lisnacreight Yr: 1834-Ardstraw-Tyrone
Semple, John-County: Down Townland: Ballyinagin Year: 1834-Magheralin-Armagh
Semple, John-T: Mulnabreen Y: 1826-Termonamongan-Tyrone
Semple, John-Townland: Ballyinagin Year: 1834-Magheralin-Down
Semple, John-Townland: Carnleagh Year: 1833- Kirkinriola -Antrim
Semple, John-Townland: Crossmarey Year: 1816-Carrickfergus-Antrim
Semple, John-Townland: Crossmary Year: 1833-Kilroots-Antrim
Semple, John-Townland: Derryduff Year: 1834-Dungiven-Derry
Semple, John-Townland: Dromore Year: 1834-Clonallan-Down
Semple, John-Townland: Loughan Year: 1834-Kildollagh-Derry
Semple, John-Townland: Narrowwater Year: 1834-Clonallan-Down
Semple, Moses-Tl: Lisnacreight Yr: 1834-Ardstraw-Tyrone
Semple, Robert-Tl: Garveteagh Lower Yr: 1834-Ardstraw-Tyrone
Semple, Robert-Tl: Lisnacreight Yr: 1834-Ardstraw-Tyrone
Semple, Samuel-Townland: Tullyhevin Year: 1833-Greyabbey-Down
Semple, Widow Townland : Carryreagh Year: 1834-Finvoy-Antrim
Semple, William-County: Down Townland: Ballyinagin Year: 1834-Magheralin-Armagh
Semple, William-Tl: Glenglush Yr: 1834-Ardstraw-Tyrone
Semple, William-Townland: Ballyinagin Year: 1834-Magheralin-Down
Semple, William-Townland: Loughan Year: 1834-Kildollagh-Derry
Semple, William-Townland: Moneydig Year: 1822-Desertoghill-Derry
Semple, Wm.-T: Moylagh Y: 1826-Clogherny-Tyrone
Semple, Wm.-Townland: Gortree Year: 1834-Clondermot-Derry
Simpel, Robert-County: Down Townland: Ballyinagin Year: 1834-Magheralin-Armagh
Simpel, Robert-Townland: Ballyinagin Year: 1834-Magheralin-Down
Simple, Adam-Townland: Whitehouse Year: 1835- Carnmoney-Antrim
Simple, Widow Tl: Derrycrush Yr: 1827--Carnteel-Tyrone
Simple, William-Townland: Carnkerk Year: 1824-Billy-Antrim
the spelling varianrs Sample, Simpel, and  Simple, found,  made me look again at Co Monaghan tithes on 
http://titheapplotmentbooks.nationalarchives.ie/search/tab/home.jsp resulting in no new entries for Co Monaghan.   Using the same website the search for anyone named Thomas Semple returns none found 
moving to
1861  Griffiths valuation three sources 1. 
https://www.failteromhat.com for quick index 
Semple   Robert      Skerrymore         Muckno   Monaghan
Semple   Thomas   Skerrymore         Muckno   Monaghan
Semple   Thomas   Castleblayney Henry St   Muckno   Monaghan
Semple   Adam      Castleblayney York St   Muckno   Monaghan
2. http://www.askaboutireland.ie/griffith-valuation/ for detail and map ref .. 
Robert has map ref 4 15 map ref 12 in Skerrymore townland
Thomas has map ref 13 in Skerrymore townland 
Thomas has map ref 4 15 in Henry st Onomy townland Castleblayney
Adam has map ref 4 20 in York st Onomy townland Castleblayney 
entries under detailsinclude thebld, office, land etc The mapa are great showing a building, fields etc around 1860. you can print them 
3. valuation-revision-books show the change of tenancy when someone moves or dies see National Archives for monaghan queries
The Semples are still there in 1911 Census see 
http://www.census.nationalarchives.ie/search/