Thanks all, 
Isabella was my G Grandmother, my grandfather her son aftershe remarried to William Wells. I managed a trip to Dumfries and was able to visit the streets where Wiliam and Isabella lived.  Also  further afield around Dumfries, where other  ancestors lived.  This  site also helped me find  a cousin 3 times removed who is in Dumfries.  Unfortunately records are a bit hit and miss beyond 1841 and much is missing beyond that because on ten paternal  line, my ancestors were originaly Irish. Whilst there are some catholic records early 1800's the key one to idenfify the parents of my  3x G Grandfather, who was born in Dumfries, do not exist.  Further  suspect many deaths due Cholera were not recorded. So I have had to make a most likely to be assmption, based of cobling together what I have.