Author Topic: DNA testing - genetic genealogy  (Read 65459 times)

Offline Redroger

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Re: DNA testing - genetic genealogy
« Reply #81 on: Monday 09 August 10 12:43 BST (UK) »
She was in fact almost 42 Marcie.
Ayres Brignell Cornwell Harvey Shipp  Stimpson Stubbings (all Cambs) Baumber Baxter Burton Ethards Proctor Stanton (all Lincs) Luffman (all counties)

Offline RJ_Paton

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Re: DNA testing - genetic genealogy
« Reply #82 on: Monday 09 August 10 13:27 BST (UK) »
Hi all,

This is probably a good site for anyone contemplating DNA testing -

http://www.worldfamilies.net/

It provides heaps of good info, which will help anyone to make an informed decision.  The University of Utah site which has already been listed in this conversation was also very good at explaining, in simple terms, how DNA works.

Tisy

There is no doubting the effectveness of DNA research - however in genealogical terms it's usefulness is limited by the very meagre take up rate and it will remain so until, or if, it ever reaches that tipping point where the databases contain details from huge numbers of researchers numbered not in their hundreds or even thousands but possibly in the millions.

Offline Shropshire Lass

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Re: DNA testing - genetic genealogy
« Reply #83 on: Monday 09 August 10 17:43 BST (UK) »
There is no doubting the effectveness of DNA research - however in genealogical terms it's usefulness is limited by the very meagre take up rate and it will remain so until, or if, it ever reaches that tipping point where the databases contain details from huge numbers of researchers numbered not in their hundreds or even thousands but possibly in the millions.

If we all wait until the databases reach that tipping point, they never will!

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Offline RJ_Paton

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Re: DNA testing - genetic genealogy
« Reply #84 on: Monday 09 August 10 18:06 BST (UK) »

If we all wait until the databases reach that tipping point, they never will!


Quite possibly but I, for one, remain firmly in the sceptics camp and have not yet heard a truly compelling argument for the "pro" group.

As an example - my surname is relatively common in at least 3 countries and yet the research group in the link listed above for this surname and several variants numbered 30 participants.


Offline nickgc

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Re: DNA testing - genetic genealogy
« Reply #85 on: Monday 09 August 10 23:08 BST (UK) »
DNA genealogy is in its absolute infancy.  The number of people who are interested in it are a tiny minority of the population, but should include all the people on this board.  Some right-wingers in the US (and perhaps other areas) say they don't answer census takers questions because it conflicts with their right to privacy.  What if our ancestors felt this way?

Watson and Crick only defined the structure of DNA in 1953.  The second sentence of their first paper was, "This structure has novel features which are of considerable biological interest."  What an understatement that turned out to be!  It took about another 10-12 years for the genetic code to be uncovered, and things have really taken off from there.  All of this has happened within the lifetime of many of us on RC.

The draft of the human genome came out in 2000, after starting only about 10 years before, and was finalized in 2003.  Using these discoveries in genealogy is really a trivial pursuit compared to the hugely important benefits that might well accrue from this research... but it should have an interest to many of us.  If science shows anything it shows that our knowledge will increase with more research.

Not too long ago, people "felt" that primates - man, chimps, orangs, gorillas, etc. - were related because they looked alike (homology).  Genetics has shown that this is a fact.  There are some strong indications that humans are more closely related to chimpanzees and bonobos than chimps are to gorillas.  All but the most stubborn people can accept this on the basis of research done on Human chromosome 2 which is a fusion of 2 separate chromosomes in other closely related primates.

I don't expect that DNA genealogy will provide much illumination of my own ancestry within my lifetime.  But the only way it ever will is if as many people who are willing to do the testing add their information to the database.

Nick 



McLellan - Inverness
Greer - Renfrewshire
Manson - Aberdeen & Orkney
Simpson - Hereford, Devon, etc.
Flett - Orkney
Chisholm - Scotland
Wishart - Orkney
Shand - Aberdeen
Pirie - Aberdeen

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Theology is never any help; it is searching in a dark cellar at midnight for a black cat that isn't there.   -Robert Heinlein

Offline Redroger

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Re: DNA testing - genetic genealogy
« Reply #86 on: Tuesday 10 August 10 17:30 BST (UK) »
DNA genealogy is in its absolute infancy.  The number of people who are interested in it are a tiny minority of the population, but should include all the people on this board.  Some right-wingers in the US (and perhaps other areas) say they don't answer census takers questions because it conflicts with their right to privacy.




[/quote

Our right wingers have another take on this, they propose abolishing the census!
Enough of that though, there is a strong possibility that I along with believed relatives in the USA may become involved in a one name DNA study in an attempt to prove that bearers of our surname on both sides of the atlantic are in fact related, documentary methods having failed. Is this a worthwhile line of approach?
Ayres Brignell Cornwell Harvey Shipp  Stimpson Stubbings (all Cambs) Baumber Baxter Burton Ethards Proctor Stanton (all Lincs) Luffman (all counties)

Offline nickgc

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Re: DNA testing - genetic genealogy
« Reply #87 on: Tuesday 10 August 10 23:29 BST (UK) »
Quote
Is this a worthwhile line of approach?

Redroger,

I'd say you have nothing to lose except a few dollars.  If you only have a small number of participants, you have less to gain.  A site I am familiar with has over 200 participants, and is quite well done as far as being able to make comparisons goes.

http://carter-cousins.org/

They have had some fairly interesting successes (described on website) and I have found 2 intriguing "possibles" to further my own line back beyond the early 1800s.  Unfortunately, one of the two has not posted a family tree so I can't do additional comparisons.

It can be a lot of work, and I suggest that you find at least one person who is dedicated to keeping the research up-to-date.

Nick
McLellan - Inverness
Greer - Renfrewshire
Manson - Aberdeen & Orkney
Simpson - Hereford, Devon, etc.
Flett - Orkney
Chisholm - Scotland
Wishart - Orkney
Shand - Aberdeen
Pirie - Aberdeen

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Theology is never any help; it is searching in a dark cellar at midnight for a black cat that isn't there.   -Robert Heinlein

Offline Tisy

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Re: DNA testing - genetic genealogy
« Reply #88 on: Tuesday 10 August 10 23:43 BST (UK) »
Hi Redroger,

This is exactly what has been done in our case - the Wood Surname DNA project at the "Smallstuff" site and the Atwood Surname Project at the Worldfamilies Site - both still small but growing;  the problem as ever is that most participants are American and most do not have a good paper trail back to the U.K.  In the case of the Wood Surname Project, most of us who are testing L20 seem to come from the midland and northern counties of England, although there are some from East Anglia.  In Steve Gilbert's research, those L20's from the midland and northern counties have been placed into the "Kingdom of Mercia Division A Cluster" and those from the South into the "Kingdom of Anglia" Cluster.  There are of course names other than Wood included in all of these projects, where the DNA is very similar.

Tisy

Offline Tisy

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Re: DNA testing - genetic genealogy
« Reply #89 on: Wednesday 11 August 10 11:10 BST (UK) »
Hi all,

This is an excerpt from Terry Barton's blog on Worldfamilies in regard to the "Family Finder" test -

"1. What type of test is this? The test constructs “autosomal blocks” using numerous SNPs in our autosomal DNA. The DNA you inherit from your parents is a mixed combination of the DNA they inherited from each of their parents. However, DNA that is close together on the chromosome tends to be inherited together. Sections of DNA that are passed on intact are called “autosomal blocks”. Your DNA consists of autosomal blocks inherited from many of your various ancestors. The more distant the ancestor, the smaller the blocks you tend to inherit from that ancestor, and the more possible it is that you will not inherit any DNA from that ancestor. By comparing the number and size of the autosomal blocks you inherit in common with other people, you can match from siblings and parents to 3rd and 4th cousins and, possibly to 5th cousins - or even further.  I am told by FTDNA that there will be no yDNA or mtDNA SNPs reported - so (unlike 23andMe) you won't get any insights on your y or mt haplogroup.  (note - I changed this last point after Raymond Wing and Steven Perkins both advised I had an error and FTDNA confirmed it)

As example - I am a 52.99% match to my Mother and a 47.67% match to my Father - which shows that the DNA evaluated by the test isn't a 50/50 blend of ancestry from my parents.  (The explanation is the inclusion of the X-Chromosome)   The 23andMe test confirmed my Deep Clade - which I already knew from Deep Clade testing at FTDNA." 

It is worth a read, and the blog can be found at the link I posted before."

Tisy