Author Topic: DNA testing - genetic genealogy  (Read 65502 times)

Offline Redroger

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Re: DNA testing - genetic genealogy
« Reply #216 on: Saturday 12 February 11 19:00 GMT (UK) »
Just taken advantage of the very good offer from Ancestry, most of the others don't really offer a discount at all after the booking fee is included. Olympia 25th Feb.
Ayres Brignell Cornwell Harvey Shipp  Stimpson Stubbings (all Cambs) Baumber Baxter Burton Ethards Proctor Stanton (all Lincs) Luffman (all counties)

Offline helvissa

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Re: DNA testing - genetic genealogy
« Reply #217 on: Saturday 19 March 11 20:40 GMT (UK) »
My boyfriend has done the DNA test and had his results back - but we're not really sure what to do with them! He went for the fullest version of the test (60-something I think) and someone else on the site is showing up all the way along but as they haven't had the test up as far, they stop at 35 (or 37... I forget).

What should he do now? He's found it interesting that his male line is halogroup J2 (very common around the Meditteranean), but... what now?

Offline DevonCruwys

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Re: DNA testing - genetic genealogy
« Reply #218 on: Saturday 19 March 11 21:25 GMT (UK) »
How exciting! I believe J2 is quite rare and is one of the haplogroups that's possibly associated with the Roman occupation of Britain. You need to make sure your boyfriend joins the haplogroup J2 project:

http://www.familytreedna.com/public/J2%20Y%20DNA%20group/default.aspx

There are other J2 projects but I think they are mostly for Jews and Arabs or for people who have taken the deep clade test which refines the subclade giving you lots of extra numbers and letters after the J2 :

http://www.isogg.org/wiki/Y-DNA_haplogroup_projects

Make sure he joins the relevant surname project, assuming there is one for his surname. (If not you could always start one!) There might also be a geographical project of interest. I've put a list of the British ones here:

http://cruwys.blogspot.com/2009/08/dna-projects-for-british-isles.html

You should be able to find the projects by logging into his personal page and then clicking on Join Projects.

From a genealogical perspective you are hoping to find close 37 and/or 67-marker matches with other people of the same or similar surnames. (Ignore all the 12- and 25-marker matches.) If so, you can compare notes with your matches and try and work out the connection. Matching DNA results will also serve to verify existing family trees. It's worth contacting the 37-marker match  to find out more about his ancestry. If it's a different surname it will probably be difficult if not impossible to find a connection. If there are no significant matches for now he just stays in the database and gets notified by e-mail of any future matches.
Researching: Ayshford, Berryman, Bodger, Boundy, Cruse, Cruwys, Dillon, Faithfull, Kennett, Keynes, Ratty, Tidbury, Trask, Westcott, Wiggins, Woolfenden.

Offline Tisy

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Re: DNA testing - genetic genealogy
« Reply #219 on: Sunday 20 March 11 00:18 GMT (UK) »
Talking of results just back, I havejust had my mtDNA (mitachondrial) results for HVR1 back.  We are in Haplogroup H with the following differences to the CRS (Cambridge Reference Standard?) -

16287T
16362C
16482G
16519C

What has really surprised me is that although "H" is very common in Western Europe (about 40% of Western Europeans are in this group) I have not one match in the ftDNA database.  I have a about 4 or 5 .1 matches on Mitosearch, none of whom have the 16287T mutation.  After looking at some research (little of which I understand!) I think it may be that we fall into the subgroup H6, which is about 40,000 years old (the oldest subgroup of H), but until I do more testing we will not know for sure. Can anyone advise whether it would be best to go for HVR2, or should be go for the full sequence?

Cheers,

Carol


Offline DevonCruwys

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Re: DNA testing - genetic genealogy
« Reply #220 on: Sunday 20 March 11 12:20 GMT (UK) »
With haplogroup H people often have literally thousands of matches with the HVR1 test. I have some people with over 8000 matches. Because of the preponderance of matches people who have upgraded to the higher-resolution tests will usually switch off the notifications for the HVR1 matches so that they don't get inundated with match e-mails.

The combined HVR1 + HVR2 test gives you results for about 1143 base pairs in the hypervariable region, otherwise known as the control region. Mutations are more likely to occur in this region. The full sequence test will give you results for all 16,569 base pairs in the mitochondrial genome. A lot of the mutations that define the different subclades are only found in the coding region. You only get the coding region results from the FGS test.

If you really want to know your subclade then the FGS is the way to go. It is however still comparatively quite expensive. FTDNA usually have an upgrade sale about once a year so it might be an idea to wait for the next one. There are about 14,000 people in the FTDNA database who have taken the FGS test (including me!) so the chances of finding a genealogically significant match are quite low. An exact FGS match is usually within a genealogical timeframe, whereas with the lower resolution tests 50% of the time a match could indicate a shared ancestor in a much deeper timeframe.

However because the test is still quite new you are effectively participating in the research. The results of FTDNA customers are helping to define the branches of the mitochondrial tree. Customers can upload their results to GenBank, a public database used by scientific researchers.

Whatever you decide make sure you join the haplogroup H project:

http://www.familytreedna.com/public/H%20mtDNA%20Haplogroup

There are subprojects for the various clades but you can only join those if you have FGS results.

Researching: Ayshford, Berryman, Bodger, Boundy, Cruse, Cruwys, Dillon, Faithfull, Kennett, Keynes, Ratty, Tidbury, Trask, Westcott, Wiggins, Woolfenden.

Offline Redroger

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Re: DNA testing - genetic genealogy
« Reply #221 on: Sunday 20 March 11 19:16 GMT (UK) »
I have had an email from FTDNA, my results should be available  around the 29th April, and I shall then know 1) which branch of the primate family I belong to? and/or 2 whether or not Homo sapiens Neanderthalensis is in fact extinct, or alive, well and living in Bournemouth. What a pity the census isn't May 1st!
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Offline nickgc

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Re: DNA testing - genetic genealogy
« Reply #222 on: Sunday 20 March 11 23:12 GMT (UK) »
Thanks for that Redroger.  I was laughing so hard after reading your point 1, that I had tears in my eyes and couldn't read the rest of your post until I left my computer for a bit.  If point 2 is proved, then we will finally have evidence that H. neanderthalensis did indeed have a sense of humor, so not all is lost.

Nick
McLellan - Inverness
Greer - Renfrewshire
Manson - Aberdeen & Orkney
Simpson - Hereford, Devon, etc.
Flett - Orkney
Chisholm - Scotland
Wishart - Orkney
Shand - Aberdeen
Pirie - Aberdeen

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Theology is never any help; it is searching in a dark cellar at midnight for a black cat that isn't there.   -Robert Heinlein

Offline Tisy

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Re: DNA testing - genetic genealogy
« Reply #223 on: Monday 21 March 11 09:31 GMT (UK) »
Many thanks for the advice and info - will go for the full sequence when I can afford it.

Cheers,

Tisy

Offline Redroger

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Re: DNA testing - genetic genealogy
« Reply #224 on: Monday 21 March 11 11:58 GMT (UK) »
Pleased you enjoyed it Nick; a putative cousin in the USA is becoming very anxious to know my results.
Ayres Brignell Cornwell Harvey Shipp  Stimpson Stubbings (all Cambs) Baumber Baxter Burton Ethards Proctor Stanton (all Lincs) Luffman (all counties)