Some thoughts....
Looking at the geographic locations of this branch of NEANDER's with AMELIA right there toowith them, I think we have to conclude there was a family relationship.
Tying them clearly to the SA family is difficult

and tying AMELIA precisely is also difficult

Who was the informant on AMELIA's death certificate?
You would think with that many of the NEANDER family around, it would be hard for there to be a mistake in the parentage listing.
There are a number of NEANDER burials at SALE Cemetery.
Of interest...... and adding to ALISON's information
NEANDER Ann.(nee WERNICKE) Aged 63 years buried 16/ 1/ 1868. Born Germany.Location not given.
This would be HANNAH, GOTTLEIB's wife.
Sue