Hmmmm...very interesting. My Catherine (Cullen) and Matthew O'Brien had the following children: Eleanor (Ellen), James, John, Daniel, Margaret, and Mary.
Of course, I realize that these are very common names, but nevertheless, Daniel and Mary are parents of Matthew with a possible brother named James. We are just missing Eleanor, John, and Margaret at this point.
By the way, is there anyone on your Cullen side that has or had asthma? My Catherine Cullen died at age 49 of asthma.
Jackie