Thank you Michael and Radcliff for all of your help, it is immensly appreciated.
The information I have got of their children is from census results that I have been following regarding their son Edward Brotherick B: 1820 and D: 1871. This is my direct relative. He married Margaret Lane B: 1820 D: 1860 in Earsdon in 1841; They had a daughter called Mary Ann Brotherick B: 1846 in Seaton Sluice M: 1868 and her death in Hartley in 1921.
She married Robert Hornsby B: 1846 Seaton Sluice and who strangely died the same year as her. Robert Hornsby was the father to Mary Robson Hornsby (My Great Great Grandmother) who married a man called James Evans.
Their daughter Catherine Ann Evans B: 1903 D: 1980 married William John Bland Clough B: 1898; their son George Evans Clough is my Grandfather.
I am researching Catherines family as her mother Mary was very abusive, but for some reason only towards Catherine- Catherine was then sent away to live with her Aunt Margaret and Uncle Jack Fenwick.
James famously left Mary, and tried to for good, owing to her abuse (some think).
The name Brotherick seems to change consistently whenever I find out new information- was this normal? A cousin of mine has found census returns where the name has changed every 10 years, which is making it very difficult to trace this family.