Is there perhaps any significance in the fact that the marriage took place in wartime?
A relative of mine was in Manchester, on "War Work" during the war, although she had no links there, one of many. I recall her telling me of how, when one of "the bunch" was getting married, and, like her, they usually came from far away, they all would rally round to provide things, and most attended the wedding, as usually the bride's family couldn't make it. I believe my relative's speciality was providing the "honeymoon suitcase"- she said it'd been on about 20 honeymoons by the time it went on her own, late in the War.
If Annie was not originally from Manchester area, but had merely been working there, then perhaps that could have accounted for a lack of family?
Don't give up - someday you'll get there, I'm sure.