Spital Hill is an extension of the Wicker - the other side of the Railway Bridge, going out of the city centre. It is a slow hill (if you see what I mean, but definitely a hill).
The 1855 old map is too early unfortunately. There is no Sheaf Street - I guess that came from the time of the railway when they must have covered up the River Sheaf. It runs underground for a mile orrso from the edge of the city centre, past (under) the (Midland) station area until it flows into the River Don. I guess that's why they called it Sheaf Street! An expert on the underground river is one Jarvis Cocker, but I don't expect he's a member of RootsChat.
There could well have been a hotel by the station. Unfortunately they built a horrible office block there (just been demolished - because they are making the area ouside the staion sexy with a massive steel winding structure and cascading fountains).
Will think on

JULIAN