Hi Shirley
Welcome to Rootschat!
I've found them in 1851, but the image is appalling

I can't find John in 1841, but he may still be in Cheshire or given his apparent occupation in 1851, he may be "in transit"!
1851 census, Manchester Deansgate, Gilbert Street
HO 107/2227 folio 784 pg 24
? Bitton; head; mar; 28; waterman; Runcorn, Cheshire
Ellen do; wife; mar; 26; Manchester
Elizabeth do; dau; 4; Manchester
Joseph do; son; 2; Manchester
Does the marriage certificate give the fathers' names, as this might make 1841 search easier?
Otherwise you'll have to post the request to the Cheshire board for John.
Regards
SandraC